Changes between Version 19 and Version 20 of ImputationPipeline
- Timestamp:
- Nov 23, 2010 2:35:34 PM (14 years ago)
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ImputationPipeline
v19 v20 112 112 == IMPUTE2 pipeline == 113 113 impute2 accepts only gen and sample files as input files. So we may have to perform some format conversions before running impute2. If our initial datasets are Ped and Map files then we can use the method: ConvertManyPedMapToGenSample to convert it to gen and sample files. If our initial datasets are in Bed/Bim/Fam format then we can use ConvertBedBimFamToPedMap to convert to Ped and Map files and then use ConvertManyPedMapToGenSample to convert to gen and sample files. As soon as you are done with these conversions steps you can use the UseImpute2WithOnePhasedReferencePanelForCompleteChromosomeInBatches to perform the imputation. This method has to be run once for each chromosome. 114 115 {{#!graphviz 116 117 digraph g { 118 a->b 119 } 120 121 }}} 114 122 === ConvertBedBimFamToPedMap === 115 123 This script converts BED, BIM, FAM files to PED and MAP by using plink. The "Path to BED, BIM, FAM file" parameter should contain the path and the suffix of these files. For example if the files are: